Connecting advocacy organizations, academia, regulatory and nonprofit organizations, I-ACT for Children develops and leads activities addressing topics aimed at improving drug development for children worldwide.
Since our inception, I-ACT for Children has engaged in a number of pre-competitive projects. Focus areas include inclusion of adolescents in adult clinical trials, COVID-related pediatric research priorities, innovations in pediatric inflammatory bowel disease (IBD) therapies and pediatric clinical trial design and development.
By engaging in pre-competitive projects, our goal is to develop innovative tools and systems that increase efficiency to benefit current and future pediatric clinical trials and researchers.
Ongoing Pre-competitive Projects
Duchenne Muscular Dystrophy Platform Trial
- A collaboration between Parent Project Muscular Dystrophy, the Critical Path Institute and I-ACT for Children to develop a platform trial that will increase access to therapeutic trials
- The trial will study multiple drugs in multiple patient types with one common placebo-controlled arm
- The goal: faster Duchenne muscular dystrophy (DMD) therapy testing and approval, as well as reduced trial startup and execution time